Evolution of Melanoma Reveals Opportunities for Intervention
UCSF researchers have identified the sequence of genetic changes that transform benign moles to into malignant skin cancer.

University of California San Francisco
UCSF researchers have identified the sequence of genetic changes that transform benign moles to into malignant skin cancer.
With a planning process underway to re-envision Parnassus Heights and a new hospital on the horizon, change to the spaces that support our learning, teaching, patient care, and research is going to be part of the UCSF experience for many years to come. A new leader is set to join UCSF in August to help manage these changes.
Margot Kushel has been announced as the new director of the UCSF Center for Vulnerable Populations at Zuckerberg San Francisco General and Trauma Center.
The already famous CRISPR system allows scientists to edit faulty genes by cutting and replacing sections of DNA, but new and improved CRISPR techniques developed at UCSF have expanded CRISPR’s scalpel into a Swiss Army knife.
Experiments using parasitic worms in the mouse gut have revealed a surprising new form of wound repair, a finding that could help scientists develop ways to enhance the body’s natural healing abilities.
Sun exposure can boost your mood, but it can also significantly boost your risk of skin cancer. Sarah Arron dispels myths around UV rays and gives you her best advice on skin protection.
For the first time, a drug derived from marijuana has been approved by the Food and Drug Administration, and it may soon offer relief to children with hard-to-treat seizures.
UCSF research team found that having less REM sleep – the sleep that includes more dreaming – was linked to higher chances of developing AF.
Insights into pitch control could pave the way for advanced brain prosthetics that could allow people who can’t speak to express themselves in a naturalistic way.
In the U.S. News annual survey for 2018-19, UCSF Benioff Children’s Hospitals’ campuses in Oakland and San Francisco placed among the country’s finest in all 10 pediatric specialties that were surveyed.
Sensory Processing Disorder, or SPD, causes some children to find everyday stimuli excruciating. Scientists are finally shedding light on what causes the disorder and what can be done about it.
A rainbow-hued contingent from UCSF turned out for the 48th annual San Francisco LGBT Pride Parade.
UCSF and a newly formed, next-generation nonprofit organization, Health Hub, are announcing their plans to affiliate.
Researchers identified a protein that cancer cells use as a shield to protect the PI3K pathway against targeted drugs, and showed that blocking this protein allowed previously ineffective therapies to slow cancer cell growth and shrink tumors.
UCSF researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs – checkpoint inhibitors.
Patricia “Pat” O’Sullivan has been named the 2018 recipient of the UCSF Lifetime Achievement in Mentoring Award.
UCSF researchers quantified the effects of Prop 47, which reclassified drug possession offenses from felonies or “wobblers”.
A so-called “jumping gene” that researchers long considered either genetic junk or a pernicious parasite is actually a critical regulator of the first stages of embryonic development.
Each year, 300,000 infants worldwide are born with sickle cell. UCSF Benioff Children’s Hospitals are at the the leading edge of advancements to cure sickle cell disease.
Scientists have used ultra-high-resolution cryo–electron microscopy to capture the most detailed portrait ever of an opioid drug triggering the biochemical signaling cascade that gives it its power.
Lloyd Hollingsworth “Holly” Smith Jr., a visionary physician-scientist whose uncompromising quest for excellence over a career spanning half a century helped transform UCSF into the world-renowned health sciences university it is today, died peacefully at his home on June 18.
UCSF has received two gifts of real estate properties that will ease the housing crunch for faculty and free up space for thriving clinical and academic programs at Mission Bay – supporting key University goals.
Forty percent of deaths attributed to cardiac arrest are not sudden or unexpected, and nearly half of the remainder are not arrhythmic – the only situation in which CPR and defibrillators are effective.
UCSF scientists have improved mobility in rats that had experienced debilitating strokes by using electrical stimulation to restore a distinctive pattern of brain cell activity associated with efficient movement.
With the June 11 opening ceremony, the University Child Care Center at Mission Bay officially becomes the largest child care center in San Francisco.
People with severe mental illness are more than twice as likely to have Type 2 diabetes, with even higher risks among patients who are African American or Hispanic, according to a new study led by UCSF.